Web30 aug. 2009 · An advanced intermediate is cyclized to give the 14-membered macrocyclic core of 6-dEB using a late-stage (step 19 of 22) C–H oxidative macrolactonization reaction that proceeds with high regio-,...

Aminoborohydrides as reducing agents. 1. Sodium …

WebThe reaction of lithium aluminum hydride with ammonia borane has been investigated in varying ratios. Evaluation of the hydrogen released, proton and boron-11 NMR … Webtetrahydrofuran is added to the suspension of lithium amidotrihydroborate via cannula over 3 min (Note 17). A quantitative transfer is effected with 5 mL of tetrahydrofuran . The ice-water bath is removed, and the reaction mixture is stirred at 23°C for 50 min. The reaction mixture is cooled to 0°C, one of the how 2 draw animals dinosaurs

Andrew Myers Department of Chemistry and Chemical Biology

Web31 jan. 2014 · Complete recovery of the staring material was observed. In contrast, lithium amidotrihydroborate affords mixtures of C–N/C–O cleavage products with similar substrates. 5d This divergent reactivity should prove useful in the selective reduction of this class of amides. Newcomb M. Tetrahedron 1993, 49, 1151. [Google Scholar] a. Web15 apr. 2002 · Lithium Amidotrihydroborate, a Powerful New Reductant. Transformation of Tertiary Amides to Primary Alcohols. A. Myers, Bryant H. Yang, D. J. Kopecky … Webwith lithium amidotrihydroborate22 provided the primary alco-hol 15 in 91% yield (12.5 g), and (R,R)-pseudoephenamine (13) was recovered in 92% yield by a simple extractive … how 2 draw animals cat