WebOct 7, 2024 · A research team led by Professor Makoto Nakanishi of the Institute of Medical Science, the University of Tokyo, generated a p16-Cre ERT2 -tdTomato mouse model … WebOct 22, 2024 · The CreERT2/loxP system is widely used to induce conditional gene deletion in mice. One of the main advantages of the system is that Cre-mediated recombination can be controlled in time through Tamoxifen administration. This has allowed researchers to study the function of embryonic lethal genes at later developmental timepoints. In …
Stem Cell Reports
WebMar 14, 2024 · The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament initially characterized in neural stem cells. However, current … WebFeb 27, 2024 · 5 Materials and Methods Mice B6.Cx3cr1CreERT2-IRES-EYFP/+ were generously provided by D. Littman (Department of Pathology, Department of Microbiology, NYU Langone Health, New York, NY 10016). B6.Rosa26stop- tdTomato mice (JAX: 007914) were from Jackson Laboratories (Bar Harbor, ME). B6.Cx3cr1CreERT2-IRES … university of texas schools list
tdTomato转基因小鼠的建系及其在细胞示踪方面的应用研究
WebNov 30, 2024 · Nestin–CreER–tdTomato mice were obtained by crossing Nestin–CreERT2 mice and B6.Cg-Gt (ROSA) 26S mice. Rag2 −/− and Rag2 −/− γc −/− mice were … Web图1. TdTomato的打靶策略[1] 这种鼠在正常情况下由于3×stop的存在并不能表达红色荧光,当与Cre鼠或TAM激活的CreERT2鼠交配后,产生的后代由于Cre重组酶切割loxp位点 … WebApr 7, 2015 · The lymphatic vascular system plays an active role in immune cell trafficking, inflammation and cancer spread. In order to provide an in vivo tool to improve our … university of texas school of law austin tx