Nis symporter
WebbThe sodium-iodide symporter (NIS) is a member of the sodium/solute symporter family that actively transports iodide across the membrane of the thyroid follicular cells. In … Webb16 jan. 2024 · The sodium iodide symporter (NIS), a transmembrane glycoprotein on the basolateral membrane of thyroid cells that actively participates in sodium and ion co …
Nis symporter
Did you know?
WebbBackground: We aimed to determine the feasibility of monitoring viral delivery and initial distribution to solid tumors using iodinated contrast agent and micro-computed tomography (CT). Methods: Human BxPC-3 pancreatic tumor xenografts were established in nude mice. An oncolytic measles virus with an additional transcriptional unit encoding the … WebbNIS sodium iodine symporter PET positron emission tomography Eur J Nucl Med Mol Imaging DOI 10.1007/s00259-008-0883-1 M. Luster (*): M. Lassmann Department of Nuclear Medicine, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, Germany e-mail: [email protected] M. Lassmann e-mail: …
WebbThe sodium-iodide symporter NIS and pendrin in iodide homeostasis of the thyroid. Endocrinol 150:1084-1090. Blanco J, Mulero M, Heredia L, Pujol A, Domingo JL, Sanchez Dc. (2013). Perinatal exposure to BDE-99 causes learning disorders and decreases serum thyroid hormone levels and BDNF gene expression in hippocampus in rat offspring. WebbThe Na+/I- symporter (NIS) catalyzes the accumulation of iodide into thyroid cells, an essential step in the biosynthesis of thyroid hormones. As a result of the isolation of the …
WebbSymporter. The NIS and active transport of iodide can be selectively inhibited by chemicals such as perchlorate and thiocyanate, thereby effectively blocking the ability of the gland to synthesize thyroid hormones. From: Handbook of Toxicologic Pathology (Second Edition), 2002. View all Topics. WebbSymporter sodowo-jodowy (NIS) zlokalizowany jest w błonie podstawnej tyreocyta. Jego fizjologiczna rola polega na katalizowaniu aktywnego, sodowo-zależnego transportu jodków z krwi do wnętrza komórki tarczycy. Gen kodujący NIS znajduje się na krótkim ramieniu chromosomu 19 w pozycji 13 (19p13) i składa się z 15 egzonów oraz 14 …
Webb3 maj 2024 · Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a powerful theranostic transgene. Novel gene therapy …
Webb8 apr. 2024 · The sodium/iodide symporter (NIS) is the essential plasma membrane protein that mediates active iodide (I-) transport into the thyroid gland, the first step in … thinkpad buttons not workingWebb15 okt. 2024 · Background: The ability of thyroid follicular epithelial cells to accumulate iodide via the sodium/iodide symporter (NIS) is exploited to successfully treat most thyroid cancers, although a subset of patients lose functional NIS activity and become unresponsive to radioiodide therapy, with poor clinical outcome. Our knowledge of NIS … thinkpad buyWebbCharakterystyka białka NIS Symporter sodowo-jodowy, nazywany także białkiem NIS (NaIS, sodium iodide symporter), odpowiada za ak-tywny transport jodu do komórki. Pierwszego odkry-cia białka NIS oraz identyfikacji jego genu dokonano w tarczycy szczurzej [1], a w 1996 roku określono se-kwencję ludzkiego genu NIS [1]. Za pomocą … thinkpad buttons wallpaperWebb3 maj 2024 · The sodium iodide symporter (NIS) is a plasma membrane glycoprotein localized at the basolateral membrane of thyroid follicular cells mediating the active … thinkpad buttonsWebbActive iodide transport into thyroid fol-licular cells is mediated by the sodium/iodide symporter (NIS), powered by Na+/K+-ATPase. NIS is expressed also in extra thyroidal tissues, most abundantly in gastric mucosa - the focus of this thesis. Cellular localisation of … thinkpad butterfly modelWebbLane 1: Mouse Stomach tissue lysates; Lane 2: Rat Stomach tissue lysates probed with NIS Polyclonal Antibody, Unconjugated (bs-0448R) at 1:200 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C. 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. thinkpad by lenovo e55WebbOncolytic virus. An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumour. [1] [2] Oncolytic viruses are thought not only to cause direct destruction of the tumour cells ... thinkpad buying ssd seperately